Anti-GCGR Monoclonal Antibody (15A11)

Subcat	Description	Isotype	Conjugate	Price
ASPC376	Anti-GCGR Antibody (15A11)	Human IgG2, Kappa	None	$460	Add
ASPC376-P	Anti-GCGR Antibody (15A11), PE	Human IgG2, Kappa	PE	$1,180	Add
ASPC376-A	Anti-GCGR Antibody (15A11), APC	Human IgG2, Kappa	APC	$980	Add
ASPC376-H	Anti-GCGR Antibody (15A11), HRP	Human IgG2, Kappa	HRP	$600	Add
ASPC376-B	Anti-GCGR Antibody (15A11), Biotin	Human IgG2, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC376

Anti-GCGR Antibody (15A11)

Human IgG2, Kappa

None

$460

Add

ASPC376-P

Anti-GCGR Antibody (15A11), PE

Human IgG2, Kappa

$1,180

Add

ASPC376-A

Anti-GCGR Antibody (15A11), APC

Human IgG2, Kappa

APC

$980

Add

ASPC376-H

Anti-GCGR Antibody (15A11), HRP

Human IgG2, Kappa

HRP

$600

Add

ASPC376-B

Anti-GCGR Antibody (15A11), Biotin

Human IgG2, Kappa

Biotin

$680

Add

Anti-GCGR Monoclonal Antibody (15A11)
- Product Description:
  
  The Anti-GCGR antibody is a human monoclonal antibody recommended for use in ELISA, flow cytometry and other applications. This antibody specifically targets GCGR and demonstrates reactivity with human, cynomolgus monkey, mouse, rat.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry
  
  Target:
  
  GCGR
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human GCGR.
  
  Immunogen:
  
  Human GCGR protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  15A11
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-GCGR Monoclonal Antibody (15A11) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

GCGR

Protein Name

Glucagon receptor

Introduction

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).

Alternative Names

GCGR; glucagon receptor; GGR; GL-RR

Gene ID

2642

UniProt

P47871

Related Disease

Mahvash disease (MVAH)

Subcellular Location

Cell membrane

Function

G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

Customer Reviews

There are no reviews for Product Name.

Submit a review and receive an Amazon gift card.

Publications

There are no publications for Product Name.

If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward