Anti-FKBP5 Monoclonal Antibody (F-4B7)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C754	Anti-FKBP5 Antibody (F-4B7)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C754

Anti-FKBP5 Antibody (F-4B7)

Mouse IgG

None

$460

Add

Anti-FKBP5 Monoclonal Antibody (F-4B7)
- Product Description:
  
  The Anti-FKBP5 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human FKBP5.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  FKBP5
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human FK506 Binding Protein 5 (FKBP5).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  F-4B7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-FKBP5 Monoclonal Antibody (F-4B7) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP5

Introduction

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Alternative Names

AIG61; FKBP54; P54; PPIase; Ptg-10; FKBP5

Gene ID

2289

UniProt

Q13451

Subcellular Location

Cytoplasm

Tissue Specificity

Widely expressed, enriched in testis compared to other tissues.

Cell Line Specificity

Cancer enhanced