Anti-FAP Monoclonal Antibody (3F2)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC098	Anti-FAP Antibody (3F2)	Human IgG1, Kappa		None	$460	In stock	Add
ASPC098-P	Anti-FAP Antibody (3F2), PE	Human IgG1, Kappa		PE	$1,180	2-3 weeks	Add
ASPC098-A	Anti-FAP Antibody (3F2), APC	Human IgG1, Kappa		APC	$980	2-3 weeks	Add
ASPC098-H	Anti-FAP Antibody (3F2), HRP	Human IgG1, Kappa		HRP	$600	2-3 weeks	Add
ASPC098-B	Anti-FAP Antibody (3F2), Biotin	Human IgG1, Kappa		Biotin	$680	2-3 weeks	Add
ASPC098-4	Anti-FAP Antibody (3F2), Fc Silenced	Human IgG1, Kappa	Fc Silenced	None	$980	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC098

Anti-FAP Antibody (3F2)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC098-P

Anti-FAP Antibody (3F2), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC098-A

Anti-FAP Antibody (3F2), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC098-H

Anti-FAP Antibody (3F2), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC098-B

Anti-FAP Antibody (3F2), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

ASPC098-4

Anti-FAP Antibody (3F2), Fc Silenced

Human IgG1, Kappa

Fc Silenced

None

$980

4-6 weeks

Add

Anti-FAP Monoclonal Antibody (3F2)
- Product Description:
  
  3F2 is a monoclonal antibody with the ability to bind fibroblast activation protein (FAP) across multiple species, including human, mouse, and cynomolgus monkey.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry
  
  Source:
  
  Mouse
  
  Target:
  
  FAP
  
  Specificity:
  
  Human, mouse and cynomolgus monkey FAP.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  3F2
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-FAP Monoclonal Antibody (3F2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

FAP

Protein Name

Prolyl endopeptidase FAP

Molecular Family

Proteases

Introduction

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Names

Fibroblast Activation Protein Alpha; Seprase; 170 KDa Melanoma Membrane-Bound Gelatinase; Gelatine Degradation Protease FAP; Integral Membrane Serine Protease; Post-Proline Cleaving Enzyme; Surface-Expressed Protease; Dipeptidyl Peptidase FAP; FAPalpha; SIMP

Gene ID

2191

UniProt

Q12884

Tissue Specificity

Expressed in adipose tissue. Expressed in the dermal fibroblasts in the fetal skin. Expressed in the granulation tissue of healing wounds and on reactive stromal fibroblast in epithelial cancers. Expressed in activated fibroblast-like synoviocytes from inflamed synovial tissues. Expressed in activated hepatic stellate cells (HSC) and myofibroblasts from cirrhotic liver, but not detected in normal liver. Expressed in glioma cells (at protein level). Expressed in glioblastomas and glioma cells. Isoform 1 and isoform 2 are expressed in melanoma, carcinoma and fibroblast cell lines.

Cell Type

Fibroblasts

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