Anti-F8 Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC1078	Anti-F8 Antibody	Human IgG1, Kappa	None	$460	Add
ASPC1078-A	Anti-F8 Antibody, APC	Human IgG1, Kappa	APC	$980	Add
ASPC1078-B	Anti-F8 Antibody, Biotin	Human IgG1, Kappa	Biotin	$680	Add
ASPC1078-H	Anti-F8 Antibody, HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC1078-P	Anti-F8 Antibody, PE	Human IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1078

Anti-F8 Antibody

Human IgG1, Kappa

None

$460

Add

ASPC1078-A

Anti-F8 Antibody, APC

Human IgG1, Kappa

APC

$980

Add

ASPC1078-B

Anti-F8 Antibody, Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC1078-H

Anti-F8 Antibody, HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC1078-P

Anti-F8 Antibody, PE

Human IgG1, Kappa

$1,180

Add

Anti-F8 Monoclonal Antibody
- Product Description:
  
  The Anti-F8 antibody is a human monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, inhibition and other applications. This antibody specifically targets F8 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Inhibition
  
  Target:
  
  F8
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human F8.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-F8 Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Coagulation factor VIII

Introduction

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Alternative Names

AHF; DXS1253EB; F8C; FVIII; HEMA; F8

Gene ID

2157

UniProt

P00451

Subcellular Location

Secreted, extracellular space.

Cell Line Specificity

Low cancer specificity

Function

Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.

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