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Anti-F7 Monoclonal Antibody (F-9H1)
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Product Description:The Anti-F7 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human F7.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:F7Target Species:HumanSpecificity:This antibody reacts with human Coagulation Factor VII (F7).Immunogen:Recombinant F7 proteinClonality:MonoclonalClone ID:F-9H1Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-F7 Monoclonal Antibody (F-9H1) Applications
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Recommended Dilution:Western Blot: 0.01-2 µg/mL
Immunohistochemistry: 5-20 µg/mL
Immunocytochemistry: 5-20 µg/mLNote:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Coagulation factor VII
Introduction
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
Alternative Names
SPCA
Gene ID
UniProt
Related Disease
Factor VII deficiency (FA7D)
Subcellular Location
Secreted
Tissue Specificity
Plasma.
Cell Line Specificity
Cancer enhanced
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