Anti-F3 Monoclonal Antibody (D3H44)

Subcat	Description	Isotype	Conjugate	Price
ASPC1077	Anti-F3 Antibody (D3H44)	Human IgG1, Kappa	None	$460	Add
ASPC1077-A	Anti-F3 Antibody (D3H44), APC	Human IgG1, Kappa	APC	$980	Add
ASPC1077-B	Anti-F3 Antibody (D3H44), Biotin	Human IgG1, Kappa	Biotin	$680	Add
ASPC1077-H	Anti-F3 Antibody (D3H44), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC1077-P	Anti-F3 Antibody (D3H44), PE	Human IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1077

Anti-F3 Antibody (D3H44)

Human IgG1, Kappa

None

$460

Add

ASPC1077-A

Anti-F3 Antibody (D3H44), APC

Human IgG1, Kappa

APC

$980

Add

ASPC1077-B

Anti-F3 Antibody (D3H44), Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC1077-H

Anti-F3 Antibody (D3H44), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC1077-P

Anti-F3 Antibody (D3H44), PE

Human IgG1, Kappa

$1,180

Add

Anti-F3 Monoclonal Antibody (D3H44)
- Product Description:
  
  The Anti-F3 antibody is a human monoclonal antibody recommended for use in immunofluorescence, enzyme-linked immunosorbent assay, western blot, neutralization, functional assay and other applications. This antibody specifically targets F3 and demonstrates reactivity with human.
  
  Applications:
  
  Immunofluorescence, Enzyme-Linked Immunosorbent Assay, Western Blot, Neutralization, Functional Assay
  
  Source:
  
  Human
  
  Target:
  
  F3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human F3.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D3H44
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-F3 Monoclonal Antibody (D3H44) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Tissue factor

Introduction

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Alternative Names

CD142; TF; TFA

Gene ID

2152

UniProt

P13726

Subcellular Location

Isoform 1: Membrane

Tissue Specificity

Lung, placenta and pancreas.

Cell Line Specificity

Cancer enhanced

Function

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

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