Anti-F2 Monoclonal Antibody (10A6)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC653	Anti-F2 Antibody (10A6)	Human IgG1, Lambda	None	$460	In stock	Add
ASPC653-P	Anti-F2 Antibody (10A6), PE	Human IgG1, Lambda	PE	$1,180	2-3 weeks	Add
ASPC653-A	Anti-F2 Antibody (10A6), APC	Human IgG1, Lambda	APC	$980	2-3 weeks	Add
ASPC653-H	Anti-F2 Antibody (10A6), HRP	Human IgG1, Lambda	HRP	$600	2-3 weeks	Add
ASPC653-B	Anti-F2 Antibody (10A6), Biotin	Human IgG1, Lambda	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC653

Anti-F2 Antibody (10A6)

Human IgG1, Lambda

None

$460

In stock

Add

ASPC653-P

Anti-F2 Antibody (10A6), PE

Human IgG1, Lambda

$1,180

2-3 weeks

Add

ASPC653-A

Anti-F2 Antibody (10A6), APC

Human IgG1, Lambda

APC

$980

2-3 weeks

Add

ASPC653-H

Anti-F2 Antibody (10A6), HRP

Human IgG1, Lambda

HRP

$600

2-3 weeks

Add

ASPC653-B

Anti-F2 Antibody (10A6), Biotin

Human IgG1, Lambda

Biotin

$680

2-3 weeks

Add

Anti-F2 Monoclonal Antibody (10A6)
- Product Description:
  
  The Anti-Thrombin antibody is a human monoclonal antibody recommended for use in ELISA, functional assay and other applications. This antibody specifically targets Thrombin and demonstrates reactivity with human, cynomolgus, rat.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay, Western Blot
  
  Target:
  
  F2
  
  Specificity:
  
  This antibody reacts with human Thrombin.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  10A6
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-F2 Monoclonal Antibody (10A6) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Introduction

This gene encodes the prothrombin protein (also known as coagulation factor II). This protein is proteolytically cleaved in multiple steps to form the activated serine protease thrombin. The activated thrombin enzyme plays an important role in thrombosis and hemostasis by converting fibrinogen to fibrin during blood clot formation, by stimulating platelet aggregation, and by activating additional coagulation factors. Thrombin also plays a role in cell proliferation, tissue repair, and angiogenesis as well as maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in this gene lead to various forms of thrombosis and dysprothrombinemia. Rapid increases in cytokine levels following coronavirus infections can dysregulate the coagulation cascade and produce thrombosis, compromised blood supply, and organ failure.

Alternative Names

PT; THPH1; RPRGL2

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