Anti-ESR1 Monoclonal Antibody (JS34/32)

Subcat	Description	Isotype	Conjugate	Price
ASPC1069	Anti-ESR1 Antibody (JS34/32)	Mouse IgG2b, Kappa	None	$460	Add
ASPC1069-A	Anti-ESR1 Antibody (JS34/32), APC	Mouse IgG2b, Kappa	APC	$980	Add
ASPC1069-B	Anti-ESR1 Antibody (JS34/32), Biotin	Mouse IgG2b, Kappa	Biotin	$680	Add
ASPC1069-H	Anti-ESR1 Antibody (JS34/32), HRP	Mouse IgG2b, Kappa	HRP	$600	Add
ASPC1069-P	Anti-ESR1 Antibody (JS34/32), PE	Mouse IgG2b, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1069

Anti-ESR1 Antibody (JS34/32)

Mouse IgG2b, Kappa

None

$460

Add

ASPC1069-A

Anti-ESR1 Antibody (JS34/32), APC

Mouse IgG2b, Kappa

APC

$980

Add

ASPC1069-B

Anti-ESR1 Antibody (JS34/32), Biotin

Mouse IgG2b, Kappa

Biotin

$680

Add

ASPC1069-H

Anti-ESR1 Antibody (JS34/32), HRP

Mouse IgG2b, Kappa

HRP

$600

Add

ASPC1069-P

Anti-ESR1 Antibody (JS34/32), PE

Mouse IgG2b, Kappa

$1,180

Add

Anti-ESR1 Monoclonal Antibody (JS34/32)
- Product Description:
  
  The Anti-ESR1 antibody is a mouse monoclonal antibody recommended for use in immunohistochemistry, immunoprecipitation, functional assay and other applications. This antibody specifically targets ESR1 and demonstrates reactivity with Bovine, Rat, Human.
  
  Applications:
  
  Immunohistochemistry, Immunoprecipitation, Functional Assay
  
  Target:
  
  ESR1
  
  Specificity:
  
  This antibody reacts with ESR1.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  JS34/32
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ESR1 Monoclonal Antibody (JS34/32) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ESR1

Protein Name

Estrogen receptor

Introduction

This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis.

Alternative Names

ESR1; ESR; ER; NR3A1; Estrogen receptor; ER-alpha; Estradiol receptor

Gene ID

407238

UniProt

P49884

Subcellular Location

Nucleus

Function

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

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