Anti-EPCAM Monoclonal Antibody (UBS-54)

Subcat	Description	Isotype	Conjugate	Price
ASPC596	Anti-EPCAM Antibody (UBS-54)	Human IgG1, Kappa	None	$460	Add
ASPC596-P	Anti-EPCAM Antibody (UBS-54), PE	Human IgG1, Kappa	PE	$1,180	Add
ASPC596-A	Anti-EPCAM Antibody (UBS-54), APC	Human IgG1, Kappa	APC	$980	Add
ASPC596-H	Anti-EPCAM Antibody (UBS-54), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC596-B	Anti-EPCAM Antibody (UBS-54), Biotin	Human IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC596

Anti-EPCAM Antibody (UBS-54)

Human IgG1, Kappa

None

$460

Add

ASPC596-P

Anti-EPCAM Antibody (UBS-54), PE

Human IgG1, Kappa

$1,180

Add

ASPC596-A

Anti-EPCAM Antibody (UBS-54), APC

Human IgG1, Kappa

APC

$980

Add

ASPC596-H

Anti-EPCAM Antibody (UBS-54), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC596-B

Anti-EPCAM Antibody (UBS-54), Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-EPCAM Monoclonal Antibody (UBS-54)
- Product Description:
  
  The Anti-EPCAM antibody is a human monoclonal antibody recommended for use in ELISA, flow cytometry, functional assay and other applications. This antibody specifically targets EPCAM and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Functional Assay, Western Blot
  
  Target:
  
  EPCAM
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human EPCAM.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  UBS-54
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-EPCAM Monoclonal Antibody (UBS-54) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

EPCAM

Protein Name

Epithelial cell adhesion molecule

Introduction

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Alternative Names

EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1

Gene ID

4072

UniProt

P16422

Molecule Mass

Adhesion Molecules, CD Molecules

Related Disease

Diarrhea 5, with tufting enteropathy, congenital (DIAR5)

Subcellular Location

Lateral cell membrane

Cell Line Specificity

Cancer enhanced

Function

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

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