Anti-EPCAM Monoclonal Antibody (2B9)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC348	Anti-EPCAM Antibody (2B9)	Mouse IgG2a, Kappa	None	$460	In stock	Add
ASPC348-P	Anti-EPCAM Antibody (2B9), PE	Mouse IgG2a, Kappa	PE	$1,180	2-3 weeks	Add
ASPC348-A	Anti-EPCAM Antibody (2B9), APC	Mouse IgG2a, Kappa	APC	$980	2-3 weeks	Add
ASPC348-H	Anti-EPCAM Antibody (2B9), HRP	Mouse IgG2a, Kappa	HRP	$600	2-3 weeks	Add
ASPC348-B	Anti-EPCAM Antibody (2B9), Biotin	Mouse IgG2a, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC348

Anti-EPCAM Antibody (2B9)

Mouse IgG2a, Kappa

None

$460

In stock

Add

ASPC348-P

Anti-EPCAM Antibody (2B9), PE

Mouse IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC348-A

Anti-EPCAM Antibody (2B9), APC

Mouse IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC348-H

Anti-EPCAM Antibody (2B9), HRP

Mouse IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC348-B

Anti-EPCAM Antibody (2B9), Biotin

Mouse IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-EPCAM Monoclonal Antibody (2B9)
- Product Description:
  
  The Anti-EPCAM antibody is a mouse monoclonal antibody recommended for use in flow cytometry, functional assay, inhibition, western blot and other applications. This antibody specifically targets EPCAM and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Functional Assay, Inhibition, Western Blot
  
  Target:
  
  EPCAM
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human EPCAM.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  2B9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-EPCAM Monoclonal Antibody (2B9) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

EPCAM

Protein Name

Epithelial cell adhesion molecule

Introduction

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Alternative Names

EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1

Gene ID

4072

UniProt

P16422

Molecule Mass

Adhesion Molecules, CD Molecules

Related Disease

Diarrhea 5, with tufting enteropathy, congenital (DIAR5)

Subcellular Location

Lateral cell membrane

Cell Line Specificity

Cancer enhanced

Function

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

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