Anti-EGFRvIII Monoclonal Antibody (1A9)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC345	Anti-EGFRvIII Antibody (1A9)	Mouse IgG2b, Kappa	None	$460	In stock	Add
ASPC345-P	Anti-EGFRvIII Antibody (1A9), PE	Mouse IgG2b, Kappa	PE	$1,180	2-3 weeks	Add
ASPC345-A	Anti-EGFRvIII Antibody (1A9), APC	Mouse IgG2b, Kappa	APC	$980	2-3 weeks	Add
ASPC345-H	Anti-EGFRvIII Antibody (1A9), HRP	Mouse IgG2b, Kappa	HRP	$600	2-3 weeks	Add
ASPC345-B	Anti-EGFRvIII Antibody (1A9), Biotin	Mouse IgG2b, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC345

Anti-EGFRvIII Antibody (1A9)

Mouse IgG2b, Kappa

None

$460

In stock

Add

ASPC345-P

Anti-EGFRvIII Antibody (1A9), PE

Mouse IgG2b, Kappa

$1,180

2-3 weeks

Add

ASPC345-A

Anti-EGFRvIII Antibody (1A9), APC

Mouse IgG2b, Kappa

APC

$980

2-3 weeks

Add

ASPC345-H

Anti-EGFRvIII Antibody (1A9), HRP

Mouse IgG2b, Kappa

HRP

$600

2-3 weeks

Add

ASPC345-B

Anti-EGFRvIII Antibody (1A9), Biotin

Mouse IgG2b, Kappa

Biotin

$680

2-3 weeks

Add

Anti-EGFRvIII Monoclonal Antibody (1A9)
- Product Description:
  
  The Anti-EGFRvIII antibody is a mouse monoclonal antibody recommended for use in functional assay and other applications. This antibody specifically targets EGFRvIII and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay
  
  Target:
  
  EGFRvIII
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human EGFRvIII.
  
  Immunogen:
  
  A peptide
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  1A9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-EGFRvIII Monoclonal Antibody (1A9) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

EGFR

Protein Name

Epidermal growth factor receptor

Introduction

EGF receptor variant III (EGFRvIII) is the most common variant of the EGF receptor observed in human tumors.

Alternative Names

EGFRvIII; Epidermal growth factor receptor variant III

Gene ID

1956

UniProt

P00533

Molecule Mass

CD Molecules, Growth Factors

Related Disease

Lung cancer (LNCR)

Subcellular Location

Cell membrane

Tissue Specificity

Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.

Cell Line Specificity

Low cancer specificity

Function

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Plays a role in enhancing learning and memory performance (By similarity). Plays a role in mammalian pain signaling (long-lasting hypersensitivity) (By similarity).

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