Anti-DSG1 Monoclonal Antibody (14H11)

Subcat	Description	Isotype	Conjugate	Price
ASPC850	Anti-DSG1 Antibody (14H11)	Human IgG1, Kappa	None	$460	Add
ASPC850-P	Anti-DSG1 Antibody (14H11), PE	Human IgG1, Kappa	PE	$1,180	Add
ASPC850-A	Anti-DSG1 Antibody (14H11), APC	Human IgG1, Kappa	APC	$980	Add
ASPC850-H	Anti-DSG1 Antibody (14H11), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC850-B	Anti-DSG1 Antibody (14H11), Biotin	Human IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC850

Anti-DSG1 Antibody (14H11)

Human IgG1, Kappa

None

$460

Add

ASPC850-P

Anti-DSG1 Antibody (14H11), PE

Human IgG1, Kappa

$1,180

Add

ASPC850-A

Anti-DSG1 Antibody (14H11), APC

Human IgG1, Kappa

APC

$980

Add

ASPC850-H

Anti-DSG1 Antibody (14H11), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC850-B

Anti-DSG1 Antibody (14H11), Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-DSG1 Monoclonal Antibody (14H11)
- Product Description:
  
  The Anti-DSG1 antibody is a human monoclonal antibody recommended for use in ELISA, western blot and other applications. This antibody specifically targets DSG1 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Target:
  
  DSG1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human DSG1.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  14H11
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-DSG1 Monoclonal Antibody (14H11) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

DSG1

Protein Name

Desmoglein-1

Introduction

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Alternative Names

DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA

Gene ID

1828

UniProt

Q02413

Related Disease

Palmoplantar keratoderma 1, striate, focal, or diffuse (PPKS1)

Subcellular Location

Cell membrane

Tissue Specificity

Epidermis, tongue, tonsil and esophagus.

Cell Line Specificity

Cancer enhanced

Function

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

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