Anti-DHODH Monoclonal Antibody (F-4B3)

Anti-DHODH Monoclonal Antibody (F-4B3)

Cat No: ASZ1C577

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
F-4B3
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C577 Anti-DHODH Antibody (F-4B3) Mouse IgG None $460
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  • Anti-DHODH Monoclonal Antibody (F-4B3)
    • Product Description:
      The Anti-DHODH antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human DHODH.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      DHODH
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Dihydroorotate Dehydrogenase (Quinone) (DHODH).
      Clonality:
      Monoclonal
      Clone ID:
      F-4B3
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-DHODH Monoclonal Antibody (F-4B3) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Dihydroorotate dehydrogenase
Introduction
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
Alternative Names
DHOdehase; POADS; URA1
Gene ID
UniProt
Related Disease
Postaxial acrofacial dysostosis (POADS)
Subcellular Location
Mitochondrion inner membrane
Cell Line Specificity
Low cancer specificity
Function
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
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