Anti-D2HGDH Monoclonal Antibody (G-1B9)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C542	Anti-D2HGDH Antibody (G-1B9)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C542

Anti-D2HGDH Antibody (G-1B9)

Mouse IgG

None

$460

Add

Anti-D2HGDH Monoclonal Antibody (G-1B9)
- Product Description:
  
  The Anti-D2HGDH antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human D2HGDH.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  D2HGDH
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human D-2-Hydroxyglutarate Dehydrogenase (D2HGDH).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  G-1B9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-D2HGDH Monoclonal Antibody (G-1B9) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

D-2-hydroxyglutarate dehydrogenase, mitochondrial

Introduction

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.

Alternative Names

D2HGD

Gene ID

728294

UniProt

Q8N465

Related Disease

D-2-hydroxyglutaric aciduria 1 (D2HGA1)

Subcellular Location

Mitochondrion

Cell Line Specificity

Low cancer specificity