-
Anti-CPZ Monoclonal Antibody (G-5E11)
-
Product Description:The Anti-CPZ antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human CPZ.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:CPZTarget Species:HumanSpecificity:This antibody reacts with human Carboxypeptidase Z (CPZ).Clonality:MonoclonalClone ID:G-5E11Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
-
-
Anti-CPZ Monoclonal Antibody (G-5E11) Applications
-
Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
-
Protein Name
Carboxypeptidase Z
Introduction
This gene encodes a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.
Alternative Names
Carboxypeptidase Z; Metallocarboxypeptidase Z; EC 3.4.17.10; EC 3.4.17.3; EC 3.4.17.-; EC 3.4.17
Gene ID
UniProt
Subcellular Location
Secreted, extracellular space, extracellular matrix
Tissue Specificity
In placenta, it is present within invasive trophoblasts and in the surrounding extracellular space. Also present in amnion cells, but is not readily apparent in the extracellular matrix of this cell type. Present in normal pituitary gland and neoplastic pituitary gland (especially POMC-, GH- and PRL-producing adenomas) (at protein level). Widely expressed.
Cell Line Specificity
Low cancer specificity
Function
Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing.
Customer Reviews
There are no reviews for Product Name.
Submit a review and receive an Amazon gift card.
Publications
There are no publications for Product Name.
If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward
