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Anti-CPT1A Monoclonal Antibody (F-3A9)
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Product Description:The Anti-CPT1A antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human CPT1A.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:CPT1ATarget Species:HumanSpecificity:This antibody reacts with human Carnitine Palmitoyltransferase 1A (CPT1A).Clonality:MonoclonalClone ID:F-3A9Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-CPT1A Monoclonal Antibody (F-3A9) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Carnitine O-palmitoyltransferase 1, liver isoform
Introduction
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Names
CPT1; CPT1-L; L-CPT1
Gene ID
UniProt
Related Disease
Carnitine palmitoyltransferase 1A deficiency (CPT1AD)
Subcellular Location
Mitochondrion outer membrane
Tissue Specificity
Strong expression in kidney and heart, and lower in liver and skeletal muscle.
Cell Line Specificity
Low cancer specificity
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