Anti-COL2A1 Monoclonal Antibody (M2139)

Subcat	Description	Isotype	Conjugate	Price
ASPC1000	Anti-COL2A1 Antibody (M2139)	Mouse IgG2b, Kappa	None	$460	Add
ASPC1000-A	Anti-COL2A1 Antibody (M2139), APC	Mouse IgG2b, Kappa	APC	$980	Add
ASPC1000-B	Anti-COL2A1 Antibody (M2139), Biotin	Mouse IgG2b, Kappa	Biotin	$680	Add
ASPC1000-H	Anti-COL2A1 Antibody (M2139), HRP	Mouse IgG2b, Kappa	HRP	$600	Add
ASPC1000-P	Anti-COL2A1 Antibody (M2139), PE	Mouse IgG2b, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1000

Anti-COL2A1 Antibody (M2139)

Mouse IgG2b, Kappa

None

$460

Add

ASPC1000-A

Anti-COL2A1 Antibody (M2139), APC

Mouse IgG2b, Kappa

APC

$980

Add

ASPC1000-B

Anti-COL2A1 Antibody (M2139), Biotin

Mouse IgG2b, Kappa

Biotin

$680

Add

ASPC1000-H

Anti-COL2A1 Antibody (M2139), HRP

Mouse IgG2b, Kappa

HRP

$600

Add

ASPC1000-P

Anti-COL2A1 Antibody (M2139), PE

Mouse IgG2b, Kappa

$1,180

Add

Anti-COL2A1 Monoclonal Antibody (M2139)
- Product Description:
  
  The Anti-COL2A1 antibody is a mouse monoclonal antibody recommended for use in immunohistochemistry-frozen, immunohistochemistry, enzyme-linked immunosorbent assay, blocking, functional assay and other applications. This antibody specifically targets COL2A1 and demonstrates reactivity with Mouse, Human, Rat, Bovine, chicken.
  
  Applications:
  
  Immunohistochemistry-Frozen, Immunohistochemistry, Enzyme-Linked Immunosorbent Assay, Blocking, Functional Assay
  
  Source:
  
  Mouse
  
  Target:
  
  COL2A1
  
  Target Species:
  
  Rat
  
  Specificity:
  
  This antibody reacts with COL2A1.
  
  Immunogen:
  
  Rat Collagen II (CII).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  M2139
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-COL2A1 Monoclonal Antibody (M2139) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

COL2A1

Protein Name

Collagen alpha-1

Introduction

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

Alternative Names

ANFH; AOM; COL11A3; SEDC; STL1

Gene ID

1280

UniProt

P02458

Subcellular Location

Secreted, extracellular space, extracellular matrix

Tissue Specificity

Isoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte.

Cell Line Specificity

Cancer enriched

Function

Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.

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