Anti-COL11A1 Monoclonal Antibody (D-9F4)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C429	Anti-COL11A1 Antibody (D-9F4)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C429

Anti-COL11A1 Antibody (D-9F4)

Mouse IgG

None

$460

Add

Anti-COL11A1 Monoclonal Antibody (D-9F4)
- Product Description:
  
  The Anti-COL11A1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human COL11A1.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  COL11A1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Collagen Type XI Alpha 1 Chain (COL11A1).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D-9F4
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-COL11A1 Monoclonal Antibody (D-9F4) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Collagen alpha-1(XI) chain

Introduction

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.

Alternative Names

CO11A1; COLL6; STL2

Gene ID

1301

UniProt

P12107

Related Disease

Stickler syndrome 2 (STL2)

Subcellular Location

Secreted, extracellular space, extracellular matrix

Tissue Specificity

Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon.

Cell Line Specificity

Cancer enhanced

Function

May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.

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