Anti-CLDN5 Monoclonal Antibody (C-10B10)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C409	Anti-CLDN5 Antibody (C-10B10)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C409

Anti-CLDN5 Antibody (C-10B10)

Mouse IgG

None

$460

Add

Anti-CLDN5 Monoclonal Antibody (C-10B10)
- Product Description:
  
  The Anti-CLDN5 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human CLDN5.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  CLDN5
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Claudin 5 (CLDN5).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C-10B10
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CLDN5 Monoclonal Antibody (C-10B10) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Claudin-5

Introduction

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative Names

AWAL; BEC1; CPETRL1; TMVCF

Gene ID

7122

UniProt

O00501

Subcellular Location

Cell junction, tight junction

Cell Line Specificity

Cancer enhanced

Function

Plays a major role in tight junction-specific obliteration of the intercellular space.