Anti-CLDN3 Monoclonal Antibody (14B11)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC331	Anti-CLDN3 Antibody (14B11)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC331-P	Anti-CLDN3 Antibody (14B11), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC331-A	Anti-CLDN3 Antibody (14B11), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC331-H	Anti-CLDN3 Antibody (14B11), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC331-B	Anti-CLDN3 Antibody (14B11), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC331

Anti-CLDN3 Antibody (14B11)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC331-P

Anti-CLDN3 Antibody (14B11), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC331-A

Anti-CLDN3 Antibody (14B11), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC331-H

Anti-CLDN3 Antibody (14B11), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC331-B

Anti-CLDN3 Antibody (14B11), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-CLDN3 Monoclonal Antibody (14B11)
- Product Description:
  
  The Anti-CLDN3 antibody is a human monoclonal antibody recommended for use in cytotoxicity assay, flow cytometry, inhibition and other applications. This antibody specifically targets CLDN3 and demonstrates reactivity with human.
  
  Applications:
  
  Cytotoxicity Assay, Flow Cytometry, Inhibition
  
  Target:
  
  CLDN3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human CLDN3 (claudin 3).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  14B11
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CLDN3 Monoclonal Antibody (14B11) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CLDN3

Protein Name

Claudin-3

Introduction

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Alternative Names

RVP1; HRVP1; C7orf1; CPE-R2; CPETR2; CLDN3

Gene ID

1365

UniProt

O15551

Subcellular Location

Cell junction, tight junction

Cell Line Specificity

Cancer enhanced

Function

Barrier-forming claudin. Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

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