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Anti-CEACAM1 Monoclonal Antibody (6G5J)
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Product Description:The Anti-CEACAM1/3/5/6/8 antibody is a mouse monoclonal antibody recommended for use in ELISA, flow cytometry and other applications. This antibody specifically targets CEACAM1/3/5/6/8 and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western BlotTarget:CEACAM1Target Species:HumanSpecificity:This antibody reacts with human CEACAM1/3/5/6/8.Immunogen:Human CEACAM1 proteinClonality:MonoclonalClone ID:6G5JPurification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-CEACAM1 Monoclonal Antibody (6G5J) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
CEACAM1
Protein Name
Cell adhesion molecule CEACAM1
Introduction
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
Alternative Names
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein); CD66a Antigen; BGP1; BGP; Biliary Glycoprotein; Antigen CD66; BGP-1; BGPI
Gene ID
UniProt
Molecule Mass
Adhesion Molecules, CD Molecules
Subcellular Location
[Isoform 1]: Cell membrane
Cell Line Specificity
Low cancer specificity
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