Anti-CDA Monoclonal Antibody (D-14A5)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C334	Anti-CDA Antibody (D-14A5)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C334

Anti-CDA Antibody (D-14A5)

Mouse IgG

None

$460

Add

Anti-CDA Monoclonal Antibody (D-14A5)
- Product Description:
  
  The Anti-CDA antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human CDA.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  CDA
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Cytidine Deaminase (CDA).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D-14A5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CDA Monoclonal Antibody (D-14A5) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Cytidine deaminase

Introduction

This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Alternative Names

CDD

Gene ID

978

UniProt

P32320

Tissue Specificity

Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.

Cell Line Specificity

Cancer enhanced

Function

This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.