Anti-CD74 Monoclonal Antibody (Lym-1)

Anti-CD74 Monoclonal Antibody (Lym-1)

Cat No: ASPF57

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunoprecipitation, Radioimmunoassay, Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Clone ID:
Lym-1
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASPF57 Anti-CD74 Antibody (Lym-1) Mouse IgG2a None $460
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ASPF57-A Anti-CD74 Antibody (Lym-1), APC Mouse IgG2a APC $980
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ASPF57-B Anti-CD74 Antibody (Lym-1), Biotin Mouse IgG2a Biotin $680
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ASPF57-H Anti-CD74 Antibody (Lym-1), HRP Mouse IgG2a HRP $600
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ASPF57-P Anti-CD74 Antibody (Lym-1), PE Mouse IgG2a PE $1,180
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-CD74 Monoclonal Antibody (Lym-1)
    • Product Description:
      This product is a mouse monoclonal antibody (clone Lym-1) that binds human CD74 (MHC-II invariant chain), is validated in RIA, ELISA, Western blot, immunoprecipitation, flow cytometry, immunofluorescence and immunohistochemistry, is azide-free, and supports both diagnostic imaging and lymphoma-targeting research.
      Applications:
      Immunoprecipitation, Radioimmunoassay, Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
      Source:
      Mouse
      Target:
      CD74
      Target Species:
      Human
      Specificity:
      This antibody reacts with Human CD74.
      Immunogen:
      Tumor cell nuclei preparations as immunogens.
      Clonality:
      Monoclonal
      Clone ID:
      Lym-1
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-CD74 Monoclonal Antibody (Lym-1) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
CD74
Protein Name
CD74 Molecule
Introduction
CD74 (CD74 Molecule) is a Protein Coding gene. Diseases associated with CD74 include Undifferentiated Pleomorphic Sarcoma and Mantle Cell Lymphoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding and amyloid-beta binding.
Alternative Names
CD74 Molecule; CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain; HLA-DR Antigens-Associated Invariant Chain; Gamma Chain Of Class II Antigens; Ia-Associated Invariant Chain; MHC HLA-DR Gamma Chain; HLA-DR-Gamma; DHLAG
Gene ID
UniProt
Related Disease
Cancers; Autoimmune diseases; Infection; Inflammation
Subcellular Location
Cell membrane, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome, Membrane
Tissue Specificity
Tissue enhanced (Lymphoid tissue)
Cell Line Specificity
Group enriched (Leukemia, Lymphoma, Myeloma, Skin cancer)
Function
The invariant chain of MHC class II molecules.
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