Anti-CD40 Monoclonal Antibody (2C5)

Subcat	Description	Isotype	Conjugate	Price
ASPC962	Anti-CD40 Antibody (2C5)	Mouse IgG1, Kappa	None	$460	Add
ASPC962-A	Anti-CD40 Antibody (2C5), APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC962-B	Anti-CD40 Antibody (2C5), Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC962-H	Anti-CD40 Antibody (2C5), HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC962-P	Anti-CD40 Antibody (2C5), PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC962

Anti-CD40 Antibody (2C5)

Mouse IgG1, Kappa

None

$460

Add

ASPC962-A

Anti-CD40 Antibody (2C5), APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC962-B

Anti-CD40 Antibody (2C5), Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC962-H

Anti-CD40 Antibody (2C5), HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC962-P

Anti-CD40 Antibody (2C5), PE

Mouse IgG1, Kappa

$1,180

Add

Anti-CD40 Monoclonal Antibody (2C5)
- Product Description:
  
  The Anti-CD40 antibody is a mouse monoclonal antibody recommended for use in immunofluorescence, flow cytometry, activation and other applications. This antibody specifically targets CD40 and demonstrates reactivity with chicken.
  
  Applications:
  
  Immunofluorescence, Flow Cytometry, Activation
  
  Target:
  
  CD40
  
  Target Species:
  
  Chicken
  
  Specificity:
  
  This antibody reacts with CD40.
  
  Immunogen:
  
  The extracellular domain of Chicken CD40.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  2C5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD40 Monoclonal Antibody (2C5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD40

Protein Name

Tumor necrosis factor receptor superfamily member 5

Introduction

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3).

Alternative Names

CD40; p50; Bp50; CDW40; TNFRSF5

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