Anti-CD40 Monoclonal Antibody (13H9)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC830	Anti-CD40 Antibody (13H9)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC830-P	Anti-CD40 Antibody (13H9), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC830-A	Anti-CD40 Antibody (13H9), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC830-H	Anti-CD40 Antibody (13H9), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC830-B	Anti-CD40 Antibody (13H9), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC830

Anti-CD40 Antibody (13H9)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC830-P

Anti-CD40 Antibody (13H9), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC830-A

Anti-CD40 Antibody (13H9), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC830-H

Anti-CD40 Antibody (13H9), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC830-B

Anti-CD40 Antibody (13H9), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-CD40 Monoclonal Antibody (13H9)
- Product Description:
  
  The Anti-CD40 antibody is a human monoclonal antibody recommended for use in blocking, cytotoxicity assay, functional assay, inhibition and other applications. This antibody specifically targets CD40 and demonstrates reactivity with human.
  
  Applications:
  
  Cytotoxicity Assay, Functional Assay, Inhibition, Western Blot
  
  Target:
  
  CD40
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human CD40.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  13H9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD40 Monoclonal Antibody (13H9) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD40

Protein Name

Tumor necrosis factor receptor superfamily member 5

Introduction

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3).

Alternative Names

CD40; p50; Bp50; CDW40; TNFRSF5

Gene ID

958

UniProt

P25942

Molecule Mass

CD Molecules

Related Disease

Immunodeficiency with hyper-IgM 3 (HIGM3)

Tissue Specificity

B-cells and in primary carcinomas.

Cell Line Specificity

Cancer enhanced

Function

Receptor for TNFSF5/CD40LG.

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