Anti-CD3E Monoclonal Antibody (YTH 12.5)

Subcat	Description	Isotype	Conjugate	Price
ASPC959	Anti-CD3E Antibody (YTH 12.5)	Rat IgG2b, Lambda	None	$460	Add
ASPC959-A	Anti-CD3E Antibody (YTH 12.5), APC	Rat IgG2b, Lambda	APC	$980	Add
ASPC959-B	Anti-CD3E Antibody (YTH 12.5), Biotin	Rat IgG2b, Lambda	Biotin	$680	Add
ASPC959-H	Anti-CD3E Antibody (YTH 12.5), HRP	Rat IgG2b, Lambda	HRP	$600	Add
ASPC959-P	Anti-CD3E Antibody (YTH 12.5), PE	Rat IgG2b, Lambda	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC959

Anti-CD3E Antibody (YTH 12.5)

Rat IgG2b, Lambda

None

$460

Add

ASPC959-A

Anti-CD3E Antibody (YTH 12.5), APC

Rat IgG2b, Lambda

APC

$980

Add

ASPC959-B

Anti-CD3E Antibody (YTH 12.5), Biotin

Rat IgG2b, Lambda

Biotin

$680

Add

ASPC959-H

Anti-CD3E Antibody (YTH 12.5), HRP

Rat IgG2b, Lambda

HRP

$600

Add

ASPC959-P

Anti-CD3E Antibody (YTH 12.5), PE

Rat IgG2b, Lambda

$1,180

Add

Anti-CD3E Monoclonal Antibody (YTH 12.5)
- Product Description:
  
  The Anti-CD3E antibody is a rat monoclonal antibody recommended for use in immunohistochemistry, immunofluorescence, western blot and other applications. This antibody specifically targets CD3E and demonstrates reactivity with human.
  
  Applications:
  
  Immunohistochemistry, Immunofluorescence, Western Blot
  
  Source:
  
  Rat
  
  Target:
  
  CD3E
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human CD3E.
  
  Immunogen:
  
  Human CD3 complex.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  YTH 12.5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD3E Monoclonal Antibody (YTH 12.5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD3E

Protein Name

T-cell surface glycoprotein CD3 epsilon chain

Introduction

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency.

Alternative Names

CD3e Molecule; CD3e Antigen, Epsilon Polypeptide (TiT3 Complex); T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e Molecule, Epsilon (CD3-TCR Complex); T3E; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3

Gene ID

916

UniProt

P07766

Subcellular Location

Cell membrane

Cell Line Specificity

Cancer enriched

Function

TCR signal transduction, T cell activation

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