Anti-CD33 Monoclonal Antibody (M195)

Subcat	Description	Isotype	Conjugate	Price
ASPC073	Anti-CD33 Antibody (M195)	Mouse IgG1, Kappa	None	$460	Add
ASPC073-P	Anti-CD33 Antibody (M195), PE	Mouse IgG1, Kappa	PE	$1,180	Add
ASPC073-A	Anti-CD33 Antibody (M195), APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC073-H	Anti-CD33 Antibody (M195), HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC073-B	Anti-CD33 Antibody (M195), Biotin	Mouse IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC073

Anti-CD33 Antibody (M195)

Mouse IgG1, Kappa

None

$460

Add

ASPC073-P

Anti-CD33 Antibody (M195), PE

Mouse IgG1, Kappa

$1,180

Add

ASPC073-A

Anti-CD33 Antibody (M195), APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC073-H

Anti-CD33 Antibody (M195), HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC073-B

Anti-CD33 Antibody (M195), Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

Anti-CD33 Monoclonal Antibody (M195)
- Product Description:
  
  The M195 antibody reacts with the human CD33 glycoprotein. CD33 is a sialic acid-binding immunoglobulin-like lectin (Siglec) family member, expressed on monocytes, myeloid progenitors, and early hematopoietic progenitor cells.
  
  Applications:
  
  Radioimmunoassay, Functional Assay, Flow Cytometry, Immunofluorescence
  
  Source:
  
  Mouse
  
  Target:
  
  CD33
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human CD33
  
  Immunogen:
  
  Live leukemic myeloblasts
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  M195
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD33 Monoclonal Antibody (M195) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD33

Protein Name

Myeloid cell surface antigen CD33

Molecular Family

CD Molecules, Siglec Molecules

Introduction

Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome.

Alternative Names

CD33 Molecule; Sialic Acid-Binding Ig-Like Lectin 3; CD33 Antigen (Gp67); SIGLEC-3; SIGLEC3; Gp67

Gene ID

945

UniProt

P20138

Subcellular Location

Nucleoplasm,Plasma membrane,Cytosol

Tissue Specificity

Monocytic/myeloid lineage cells. In the brain, CD33 is mainly expressed on microglial cells.

Cell Type

Dendritic cells, Granulocytes, Hematopoietic stem and progenitors, Mast cells, Monocytes, Neutrophils

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