Anti-CD274 Monoclonal Antibody (15A5)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC721	Anti-CD274 Antibody (15A5)	Rat IgG2a, Kappa	None	$460	In stock	Add
ASPC721-P	Anti-CD274 Antibody (15A5), PE	Rat IgG2a, Kappa	PE	$1,180	2-3 weeks	Add
ASPC721-A	Anti-CD274 Antibody (15A5), APC	Rat IgG2a, Kappa	APC	$980	2-3 weeks	Add
ASPC721-H	Anti-CD274 Antibody (15A5), HRP	Rat IgG2a, Kappa	HRP	$600	2-3 weeks	Add
ASPC721-B	Anti-CD274 Antibody (15A5), Biotin	Rat IgG2a, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC721

Anti-CD274 Antibody (15A5)

Rat IgG2a, Kappa

None

$460

In stock

Add

ASPC721-P

Anti-CD274 Antibody (15A5), PE

Rat IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC721-A

Anti-CD274 Antibody (15A5), APC

Rat IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC721-H

Anti-CD274 Antibody (15A5), HRP

Rat IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC721-B

Anti-CD274 Antibody (15A5), Biotin

Rat IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-CD274 Monoclonal Antibody (15A5)
- Product Description:
  
  The Anti-CD274 antibody is a rat monoclonal antibody recommended for use in inhibition, flow cytometry, blocking and other applications. This antibody specifically targets CD274 and demonstrates reactivity with human.
  
  Applications:
  
  Inhibition, Flow Cytometry, Blocking
  
  Target:
  
  CD274
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human CD274.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  15A5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD274 Monoclonal Antibody (15A5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD274

Protein Name

Programmed cell death 1 ligand 1

Introduction

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma.

Alternative Names

CD274; CD274 molecule; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1

Customer Reviews

There are no reviews for Product Name.

Submit a review and receive an Amazon gift card.

Publications

There are no publications for Product Name.

If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward