Anti-CD27 Monoclonal Antibody (9H3)

Subcat	Description	Isotype	Conjugate	Price
ASPC487	Anti-CD27 Antibody (9H3)	Human IgG1, Kappa	None	$460	Add
ASPC487-P	Anti-CD27 Antibody (9H3), PE	Human IgG1, Kappa	PE	$1,180	Add
ASPC487-A	Anti-CD27 Antibody (9H3), APC	Human IgG1, Kappa	APC	$980	Add
ASPC487-H	Anti-CD27 Antibody (9H3), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC487-B	Anti-CD27 Antibody (9H3), Biotin	Human IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC487

Anti-CD27 Antibody (9H3)

Human IgG1, Kappa

None

$460

Add

ASPC487-P

Anti-CD27 Antibody (9H3), PE

Human IgG1, Kappa

$1,180

Add

ASPC487-A

Anti-CD27 Antibody (9H3), APC

Human IgG1, Kappa

APC

$980

Add

ASPC487-H

Anti-CD27 Antibody (9H3), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC487-B

Anti-CD27 Antibody (9H3), Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-CD27 Monoclonal Antibody (9H3)
- Product Description:
  
  The Anti-CD27 antibody is a human monoclonal antibody recommended for use in ELISA, functional assay, western blot and other applications. This antibody specifically targets CD27 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay, Western Blot
  
  Target:
  
  CD27
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human CD27.
  
  Immunogen:
  
  Recombinant Human CD27 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  9H3
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD27 Monoclonal Antibody (9H3) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD27

Protein Name

CD27 antigen

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Alternative Names

CD27; CD27 molecule; T14; S152; Tp55; TNFRSF7; S152. LPFS2

Gene ID

939

UniProt

P26842

Molecule Mass

CD Molecules

Related Disease

Lymphoproliferative syndrome 2 (LPFS2)

Subcellular Location

Cell membrane

Tissue Specificity

Found in most T-lymphocytes.

Cell Line Specificity

Cancer enriched

Function

Costimulatory immune-checkpoint receptor expressed at the surface of T-cells, NK-cells and B-cells which binds to and is activated by its ligand CD70/CD27L expressed by B-cells.

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