Anti-CD200R1 Monoclonal Antibody (OX108)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC003	Anti-CD200R1 Antibody (OX108)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC003-P	Anti-CD200R1 Antibody (OX108), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC003-A	Anti-CD200R1 Antibody (OX108), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC003-H	Anti-CD200R1 Antibody (OX108), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC003-B	Anti-CD200R1 Antibody (OX108), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC003

Anti-CD200R1 Antibody (OX108)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC003-P

Anti-CD200R1 Antibody (OX108), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC003-A

Anti-CD200R1 Antibody (OX108), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC003-H

Anti-CD200R1 Antibody (OX108), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC003-B

Anti-CD200R1 Antibody (OX108), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-CD200R1 Monoclonal Antibody (OX108)
- Product Description:
  
  OX108 is a monoclonal antibody that specifically targets the CD200 receptor (CD200R). This receptor is involved in the regulation of immune responses and is expressed on various immune cells, including macrophages, dendritic cells, and certain lymphocyte subsets.
  
  Applications:
  
  Flow Cytometry
  
  Source:
  
  Mouse
  
  Target:
  
  CD200R1
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human CD200R
  
  Immunogen:
  
  Human CD200R protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  OX108
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD200R1 Monoclonal Antibody (OX108) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD200R1

Protein Name

Cell surface glycoprotein CD200 receptor 1

Molecular Family

CD Molecules

Introduction

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal.

Alternative Names

CD200 Receptor 1; Cell Surface Glycoprotein OX2 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; MOX2 Receptor; CD200R; MOX2R

Gene ID

131450

UniProt

Q8TD46

Subcellular Location

Plasma membrane

Tissue Specificity

Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.

Cell Type

Mast cells, Monocytes, Neutrophils, T cells

Function

Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.

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