Anti-CD200R1 Monoclonal Antibody (12B6)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC307	Anti-CD200R1 Antibody (12B6)	Rat IgG1, Kappa	None	$460	In stock	Add
ASPC307-P	Anti-CD200R1 Antibody (12B6), PE	Rat IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC307-A	Anti-CD200R1 Antibody (12B6), APC	Rat IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC307-H	Anti-CD200R1 Antibody (12B6), HRP	Rat IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC307-B	Anti-CD200R1 Antibody (12B6), Biotin	Rat IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC307

Anti-CD200R1 Antibody (12B6)

Rat IgG1, Kappa

None

$460

In stock

Add

ASPC307-P

Anti-CD200R1 Antibody (12B6), PE

Rat IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC307-A

Anti-CD200R1 Antibody (12B6), APC

Rat IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC307-H

Anti-CD200R1 Antibody (12B6), HRP

Rat IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC307-B

Anti-CD200R1 Antibody (12B6), Biotin

Rat IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-CD200R1 Monoclonal Antibody (12B6)
- Product Description:
  
  The Anti-CD200R1 antibody is a rat monoclonal antibody recommended for use in functional assay, immunoprecipitation, inhibition and other applications. This antibody specifically targets CD200R1 and demonstrates reactivity with human.
  
  Applications:
  
  Functional Assay, Immunoprecipitation, Inhibition
  
  Target:
  
  CD200R1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human CD200R1.
  
  Immunogen:
  
  Human CD200R extracellular domain
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  12B6
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CD200R1 Monoclonal Antibody (12B6) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CD200R1

Protein Name

Cell surface glycoprotein CD200 receptor 1

Introduction

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal.

Alternative Names

CD200 Receptor 1; Cell Surface Glycoprotein OX2 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; MOX2 Receptor; CD200R; MOX2R

Gene ID

131450

UniProt

Q8TD46

Molecule Mass

CD Molecules

Tissue Specificity

Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.

Cell Line Specificity

Cancer enhanced

Function

Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.

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