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Anti-CD1A Monoclonal Antibody (12C10)
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Product Description:The Anti-CD1A antibody is a human monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets CD1A and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent AssayTarget:CD1ATarget Species:HumanSpecificity:This antibody reacts with human CD1a.Clonality:MonoclonalClone ID:12C10Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-CD1A Monoclonal Antibody (12C10) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
CD1A
Protein Name
T-cell surface glycoprotein CD1a
Introduction
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Alternative Names
CD1a Molecule; T-Cell Surface Antigen T6/Leu-6; HTa1 Thymocyte Antigen; CD1a Antigen; Cortical Thymocyte Antigen CD1A; Cluster Of Differentiation 1 A; FCB6; HTA1; CD1; R4; T6
Gene ID
UniProt
Molecule Mass
CD Molecules
Subcellular Location
Cell membrane
Tissue Specificity
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
Cell Line Specificity
Cancer enriched
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
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