Anti-CCR1 Monoclonal Antibody (2C7)

Anti-CCR1 Monoclonal Antibody (2C7)

Cat No: ASPC658

Summary
Host Species:
Human
Species Reactivity:
Human, Mouse
Applications:
Flow Cytometry, Inhibition
Clone ID:
2C7
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC658 Anti-CCR1 Antibody (2C7) Human IgG4, Kappa None $460 In stock
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ASPC658-P Anti-CCR1 Antibody (2C7), PE Human IgG4, Kappa PE $1,180 2-3 weeks
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ASPC658-A Anti-CCR1 Antibody (2C7), APC Human IgG4, Kappa APC $980 2-3 weeks
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ASPC658-H Anti-CCR1 Antibody (2C7), HRP Human IgG4, Kappa HRP $600 2-3 weeks
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ASPC658-B Anti-CCR1 Antibody (2C7), Biotin Human IgG4, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-CCR1 Monoclonal Antibody (2C7)
    • Product Description:
      The Anti-CCR1 antibody is a human monoclonal antibody recommended for use in flow cytometry, inhibition and other applications. This antibody specifically targets CCR1 and demonstrates reactivity with human, mouse.
      Applications:
      Flow Cytometry, Inhibition
      Target:
      CCR1
      Specificity:
      This antibody reacts with human CCR1.
      Clonality:
      Monoclonal
      Clone ID:
      2C7
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-CCR1 Monoclonal Antibody (2C7) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
CCR1
Protein Name
C-C chemokine receptor type 1
Introduction
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite.
Alternative Names
C-C Motif Chemokine Receptor 1; CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1
Gene ID
UniProt
Molecule Mass
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Subcellular Location
Cell membrane
Tissue Specificity
Widely expressed in different hematopoietic cells.
Cell Line Specificity
Cancer enriched
Function
Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses.
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