Anti-CA9 Monoclonal Antibody (M75)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC018	Anti-CA9 Antibody (M75)	Mouse IgG2b, Kappa		None	$460	In stock	Add
ASPC018-P	Anti-CA9 Antibody (M75), PE	Mouse IgG2b, Kappa		PE	$1,180	2-3 weeks	Add
ASPC018-A	Anti-CA9 Antibody (M75), APC	Mouse IgG2b, Kappa		APC	$980	2-3 weeks	Add
ASPC018-H	Anti-CA9 Antibody (M75), HRP	Mouse IgG2b, Kappa		HRP	$600	2-3 weeks	Add
ASPC018-B	Anti-CA9 Antibody (M75), Biotin	Mouse IgG2b, Kappa		Biotin	$680	2-3 weeks	Add
ASPC018-4	Anti-CA9 Antibody (M75), Fc Silenced	Mouse IgG2b, Kappa	Fc Silenced	None	$980	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC018

Anti-CA9 Antibody (M75)

Mouse IgG2b, Kappa

None

$460

In stock

Add

ASPC018-P

Anti-CA9 Antibody (M75), PE

Mouse IgG2b, Kappa

$1,180

2-3 weeks

Add

ASPC018-A

Anti-CA9 Antibody (M75), APC

Mouse IgG2b, Kappa

APC

$980

2-3 weeks

Add

ASPC018-H

Anti-CA9 Antibody (M75), HRP

Mouse IgG2b, Kappa

HRP

$600

2-3 weeks

Add

ASPC018-B

Anti-CA9 Antibody (M75), Biotin

Mouse IgG2b, Kappa

Biotin

$680

2-3 weeks

Add

ASPC018-4

Anti-CA9 Antibody (M75), Fc Silenced

Mouse IgG2b, Kappa

Fc Silenced

None

$980

4-6 weeks

Add

Anti-CA9 Monoclonal Antibody (M75)
- Product Description:
  
  The M75 antibody has high specificity for CA IX and does not cross-react significantly with other carbonic anhydrase isoforms, making it an ideal marker for identifying CA IX expression in tissues and cell lines.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot, Immunohistochemistry
  
  Source:
  
  Mouse
  
  Target:
  
  CA9
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human carbonic anhydrase IX
  
  Immunogen:
  
  HeLa cells infected with mammary tumor cells.
  
  Epitope:
  
  LPGEEDLPG
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  M75
  
  Isotype:
  
  Mouse IgG2b, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-CA9 Monoclonal Antibody (M75) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

CA9

Protein Name

Carbonic anhydrase 9

Introduction

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.

Alternative Names

MN; CAIX; Carbonic anhydrase 9

Gene ID

768

UniProt

Q16790

Subcellular Location

Plasma membrane

Tissue Specificity

Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.

Cell Type

Tregs

Function

Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).

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