Anti-C5 Monoclonal Antibody (2G10)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC534	Anti-C5 Antibody (2G10)	Human IgG2, Kappa		None	$460	In stock	Add
ASPC534-1	Anti-C5 Antibody (2G10), scFv fragment	Human scFv	His tag	None	$460	In stock	Add
ASPC534-P	Anti-C5 Antibody (2G10), PE	Human IgG2, Kappa		PE	$1,180	2-3 weeks	Add
ASPC534-A	Anti-C5 Antibody (2G10), APC	Human IgG2, Kappa		APC	$980	2-3 weeks	Add
ASPC534-H	Anti-C5 Antibody (2G10), HRP	Human IgG2, Kappa		HRP	$600	2-3 weeks	Add
ASPC534-B	Anti-C5 Antibody (2G10), Biotin	Human IgG2, Kappa		Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC534

Anti-C5 Antibody (2G10)

Human IgG2, Kappa

None

$460

In stock

Add

ASPC534-1

Anti-C5 Antibody (2G10), scFv fragment

Human scFv

His tag

None

$460

In stock

Add

ASPC534-P

Anti-C5 Antibody (2G10), PE

Human IgG2, Kappa

$1,180

2-3 weeks

Add

ASPC534-A

Anti-C5 Antibody (2G10), APC

Human IgG2, Kappa

APC

$980

2-3 weeks

Add

ASPC534-H

Anti-C5 Antibody (2G10), HRP

Human IgG2, Kappa

HRP

$600

2-3 weeks

Add

ASPC534-B

Anti-C5 Antibody (2G10), Biotin

Human IgG2, Kappa

Biotin

$680

2-3 weeks

Add

Anti-C5 Monoclonal Antibody (2G10)
- Product Description:
  
  The Anti-C5 antibody is a human monoclonal antibody recommended for use in ELISA, blocking and other applications. This antibody specifically targets C5 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Blocking
  
  Target:
  
  C5
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human C5.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  2G10
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-C5 Monoclonal Antibody (2G10) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Complement C5

Introduction

This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC).

Alternative Names

C5, CPAMD4, Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4

Gene ID

727

UniProt

P01031

Related Disease

Complement component 5 deficiency (C5D)

Subcellular Location

Secreted.

Cell Line Specificity

Cancer enriched

Function

Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.

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