Anti-C3 Monoclonal Antibody (C3-2)

Subcat	Description	Isotype	Conjugate	Price
ASPR12	Anti-C3 Antibody (C3-2)	Mouse IgG1, Kappa	None	$530	Add
ASPR12-A	Anti-C3 Antibody (C3-2), APC	Mouse IgG1, Kappa	APC	$1,030	Add
ASPR12-B	Anti-C3 Antibody (C3-2), Biotin	Mouse IgG1, Kappa	Biotin	$760	Add
ASPR12-H	Anti-C3 Antibody (C3-2), HRP	Mouse IgG1, Kappa	HRP	$680	Add
ASPR12-P	Anti-C3 Antibody (C3-2), PE	Mouse IgG1, Kappa	PE	$1,280	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPR12

Anti-C3 Antibody (C3-2)

Mouse IgG1, Kappa

None

$530

Add

ASPR12-A

Anti-C3 Antibody (C3-2), APC

Mouse IgG1, Kappa

APC

$1,030

Add

ASPR12-B

Anti-C3 Antibody (C3-2), Biotin

Mouse IgG1, Kappa

Biotin

$760

Add

ASPR12-H

Anti-C3 Antibody (C3-2), HRP

Mouse IgG1, Kappa

HRP

$680

Add

ASPR12-P

Anti-C3 Antibody (C3-2), PE

Mouse IgG1, Kappa

$1,280

Add

Anti-C3 Monoclonal Antibody (C3-2)
- Product Description:
  
  The anti-C3 antibody is a mouse monoclonal antibody recommended for Inhibition, Surface Plasmon Resonance, Western Blot, Enzyme-Linked Immunosorbent Assay. This antibody specifically targets C3 and demonstrates reactivity with human.
  
  Applications:
  
  Inhibition, Surface Plasmon Resonance, Western Blot, Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  C3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human C3.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C3-2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  The concentration of the antibody is 1 mg/mL, but it may vary depending on the specific lot.
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Preservative:
  
  Azide free
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-C3 Monoclonal Antibody (C3-2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Complement C3

Introduction

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. A peptide (C3a) derived from the encoded protein has antimicrobial activity, so people with C3 deficiency are susceptible to bacterial infection.

Alternative Names

C3; complement component 3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; complement C3; prepro-C3; C3a anaphylatoxin; complement component C3; complement component C3a; complement component C3b

Gene ID

718

UniProt

P01024

Related Disease

Complement component 3 deficiency (C3D); Macular degeneration, age-related, 9 (ARMD9); Hemolytic uremic syndrome, atypical, 5 (AHUS5)

Subcellular Location

Secreted

Tissue Specificity

Plasma

Function

Precursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system.

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