Anti-C3 Monoclonal Antibody (16B5)

Subcat	Description	Isotype	Conjugate	Price
ASPC580	Anti-C3 Antibody (16B5)	Human IgG1, Lambda	None	$460	Add
ASPC580-P	Anti-C3 Antibody (16B5), PE	Human IgG1, Lambda	PE	$1,180	Add
ASPC580-A	Anti-C3 Antibody (16B5), APC	Human IgG1, Lambda	APC	$980	Add
ASPC580-H	Anti-C3 Antibody (16B5), HRP	Human IgG1, Lambda	HRP	$600	Add
ASPC580-B	Anti-C3 Antibody (16B5), Biotin	Human IgG1, Lambda	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC580

Anti-C3 Antibody (16B5)

Human IgG1, Lambda

None

$460

Add

ASPC580-P

Anti-C3 Antibody (16B5), PE

Human IgG1, Lambda

$1,180

Add

ASPC580-A

Anti-C3 Antibody (16B5), APC

Human IgG1, Lambda

APC

$980

Add

ASPC580-H

Anti-C3 Antibody (16B5), HRP

Human IgG1, Lambda

HRP

$600

Add

ASPC580-B

Anti-C3 Antibody (16B5), Biotin

Human IgG1, Lambda

Biotin

$680

Add

Anti-C3 Monoclonal Antibody (16B5)
- Product Description:
  
  The Anti-C3 antibody is a human monoclonal antibody recommended for use in ELISA, inhibition and other applications. This antibody specifically targets C3 and demonstrates reactivity with human and cynomolgus monkey.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Inhibition, Western Blot
  
  Target:
  
  C3
  
  Specificity:
  
  This antibody reacts with human C3.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  16B5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-C3 Monoclonal Antibody (16B5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Complement C3

Introduction

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways.

Alternative Names

ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p

Gene ID

718

UniProt

P01024

Related Disease

Complement component 3 deficiency (C3D)

Subcellular Location

Secreted.

Tissue Specificity

Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods.

Cell Line Specificity

Cancer enhanced

Function

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

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