Anti-C. botulinum BoNT/A Monoclonal Antibody (9G2)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC539	Anti-C. botulinum BoNT/A Antibody (9G2)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC539-P	Anti-C. botulinum BoNT/A Antibody (9G2), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC539-A	Anti-C. botulinum BoNT/A Antibody (9G2), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC539-H	Anti-C. botulinum BoNT/A Antibody (9G2), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC539-B	Anti-C. botulinum BoNT/A Antibody (9G2), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC539

Anti-C. botulinum BoNT/A Antibody (9G2)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC539-P

Anti-C. botulinum BoNT/A Antibody (9G2), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC539-A

Anti-C. botulinum BoNT/A Antibody (9G2), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC539-H

Anti-C. botulinum BoNT/A Antibody (9G2), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC539-B

Anti-C. botulinum BoNT/A Antibody (9G2), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-C. botulinum BoNT/A Monoclonal Antibody (9G2)
- Product Description:
  
  The Anti-C. botulinum BoNT/A antibody is a human monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets C. botulinum BoNT/A.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Target:
  
  C. botulinum BoNT/A
  
  Target Species:
  
  Clostridium botulinum
  
  Specificity:
  
  This antibody reacts with Clostridium botulinum Botulinum neurotoxin type A.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  9G2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-C. botulinum BoNT/A Monoclonal Antibody (9G2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

botA

Protein Name

Botulinum neurotoxin type A

Introduction

Botulinum neurotoxin type A is one of the seven serotypes of Botulinum Neurotoxins (BoNTs) produced by various strains of Clostridium botulinum (1, 2). BoNTs are synthesized as inactive single chain protein precursors and activated by proteolytic cleavage to generate disulfide-linked two-chain proteins. The 50 kDa light chain contains the catalytic domain, whereas the 100 kDa heavy chain contains an internal translocation domain and a receptor binding domain (3). BoNTs are the most potent protein toxins for humans. As zinc proteases, they cleave SNARE proteins to elicit flaccid paralysis in botulism by blocking acetylcholine release at the neuromuscular junction (2‑4). E. coliexpressed recombinant light chains are active proteases. However, they are not toxic because they cannot enter into host cells in the absence of the heavy chains.

Alternative Names

C. botulinum botA; Clostridium botulinum Botulinum neurotoxin type A precursor; C. botulinum; Clostridium botulinum; Botulinum neurotoxin type A precursor; botA

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