Anti-Bovine PRNP Monoclonal Antibody (12B4)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC538	Anti-PRNP Antibody (12B4)	Mouse IgG2b, Kappa	None	$460	In stock	Add
ASPC538-P	Anti-PRNP Antibody (12B4), PE	Mouse IgG2b, Kappa	PE	$1,180	2-3 weeks	Add
ASPC538-A	Anti-PRNP Antibody (12B4), APC	Mouse IgG2b, Kappa	APC	$980	2-3 weeks	Add
ASPC538-H	Anti-PRNP Antibody (12B4), HRP	Mouse IgG2b, Kappa	HRP	$600	2-3 weeks	Add
ASPC538-B	Anti-PRNP Antibody (12B4), Biotin	Mouse IgG2b, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC538

Anti-PRNP Antibody (12B4)

Mouse IgG2b, Kappa

None

$460

In stock

Add

ASPC538-P

Anti-PRNP Antibody (12B4), PE

Mouse IgG2b, Kappa

$1,180

2-3 weeks

Add

ASPC538-A

Anti-PRNP Antibody (12B4), APC

Mouse IgG2b, Kappa

APC

$980

2-3 weeks

Add

ASPC538-H

Anti-PRNP Antibody (12B4), HRP

Mouse IgG2b, Kappa

HRP

$600

2-3 weeks

Add

ASPC538-B

Anti-PRNP Antibody (12B4), Biotin

Mouse IgG2b, Kappa

Biotin

$680

2-3 weeks

Add

Anti-Bovine PRNP Monoclonal Antibody (12B4)
- Product Description:
  
  The Anti-PRNP antibody is a mouse monoclonal antibody recommended for use in immunofluorescence and other applications. This antibody specifically targets PRNP and demonstrates reactivity with Bovine.
  
  Applications:
  
  Immunofluorescence
  
  Target:
  
  PRNP
  
  Specificity:
  
  This antibody reacts with Bovine Major prion protein.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  12B4
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-Bovine PRNP Monoclonal Antibody (12B4) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PRNP

Protein Name

Major prion protein

Introduction

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp.

Alternative Names

CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C

Gene ID

281427

UniProt

F7VJQ2

Subcellular Location

Mitochondrion outer membrane

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