Anti-BMP2 Monoclonal Antibody (H-7H3)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C219	Anti-BMP2 Antibody (H-7H3)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C219

Anti-BMP2 Antibody (H-7H3)

Mouse IgG

None

$460

Add

Anti-BMP2 Monoclonal Antibody (H-7H3)
- Product Description:
  
  The Anti-BMP2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human BMP2.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  BMP2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Bone Morphogenetic Protein 2 (BMP2).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  H-7H3
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-BMP2 Monoclonal Antibody (H-7H3) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Bone morphogenetic protein 2

Introduction

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Alternative Names

BDA2A; BMP2

Gene ID

650

UniProt

P12643

Related Disease

Brachydactyly A2 (BDA2)

Subcellular Location

Secreted.

Tissue Specificity

Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Cell Line Specificity

Cancer enhanced

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