Anti-BGLAP Monoclonal Antibody (KTM219)

Subcat	Description	Isotype	Conjugate	Price
ASPC922	Anti-BGLAP Antibody (KTM219)	Mouse IgG1, Kappa	None	$460	Add
ASPC922-A	Anti-BGLAP Antibody (KTM219), APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC922-B	Anti-BGLAP Antibody (KTM219), Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC922-H	Anti-BGLAP Antibody (KTM219), HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC922-P	Anti-BGLAP Antibody (KTM219), PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC922

Anti-BGLAP Antibody (KTM219)

Mouse IgG1, Kappa

None

$460

Add

ASPC922-A

Anti-BGLAP Antibody (KTM219), APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC922-B

Anti-BGLAP Antibody (KTM219), Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC922-H

Anti-BGLAP Antibody (KTM219), HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC922-P

Anti-BGLAP Antibody (KTM219), PE

Mouse IgG1, Kappa

$1,180

Add

Anti-BGLAP Monoclonal Antibody (KTM219)
- Product Description:
  
  The Anti-BGLAP antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay and other applications. This antibody specifically targets BGLAP and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  BGLAP
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human BGLAP.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  KTM219
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-BGLAP Monoclonal Antibody (KTM219) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

BGLAP

Protein Name

Osteocalcin

Introduction

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Alternative Names

BGP; OC; OCN

Gene ID

632

UniProt

P02818

Subcellular Location

Secreted

Cell Line Specificity

Cancer enhanced

Function

Bone protein that constitutes 1-2% of the total bone protein, and which acts as a negative regulator of bone formation. Functions to limit bone formation without impairing bone resorption or mineralization (By similarity). It binds strongly to apatite and calcium.

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