Anti-BAG3 Monoclonal Antibody (F-5E10)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C192	Anti-BAG3 Antibody (F-5E10)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C192

Anti-BAG3 Antibody (F-5E10)

Mouse IgG

None

$460

Add

Anti-BAG3 Monoclonal Antibody (F-5E10)
- Product Description:
  
  The Anti-BAG3 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human BAG3.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  BAG3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human BCL2 Associated Athanogene 3 (BAG3).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  F-5E10
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-BAG3 Monoclonal Antibody (F-5E10) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

BAG family molecular chaperone regulator 3

Introduction

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Alternative Names

BAG-3; BIS; CAIR-1; MFM6

Gene ID

9531

UniProt

O95817

Related Disease

Myopathy, myofibrillar, 6 (MFM6)

Subcellular Location

Nucleus

Cell Line Specificity

Low cancer specificity