Anti-AQP4 Monoclonal Antibody (D15107)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC111	Anti-AQP4 Antibody (D15107)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC111-P	Anti-AQP4 Antibody (D15107), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC111-A	Anti-AQP4 Antibody (D15107), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC111-H	Anti-AQP4 Antibody (D15107), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC111-B	Anti-AQP4 Antibody (D15107), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC111

Anti-AQP4 Antibody (D15107)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC111-P

Anti-AQP4 Antibody (D15107), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC111-A

Anti-AQP4 Antibody (D15107), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC111-H

Anti-AQP4 Antibody (D15107), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC111-B

Anti-AQP4 Antibody (D15107), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-AQP4 Monoclonal Antibody (D15107)
- Product Description:
  
  The antibody D15107 is a monoclonal antibody that can recognize the M1 and M23 isoforms of human AQP4. This antibody can also bind to the M23 isoform of mouse AQP4 with weaker affinity.
  
  Applications:
  
  Inhibition, Immunoprecipitation, Enzyme-Linked Immunosorbent Assay, Flow Cytometry
  
  Source:
  
  Mouse
  
  Target:
  
  AQP4
  
  Target Species:
  
  Human
  
  Specificity:
  
  The extracellular domain of human aquaporin 4 (AQP4)
  
  Immunogen:
  
  Human AQP4 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D15107
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-AQP4 Monoclonal Antibody (D15107) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

AQP4

Protein Name

Aquaporin-4

Introduction

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Alternative Names

Aquaporin 4; Mercurial-Insensitive Water Channel; MIWC; WCH4; Aquaporin Type4; Aquaporin-4; AQP-4

Gene ID

361

UniProt

P55087

Related Disease

Megalencephalic leukoencephalopathy with subcortical cysts 4, remitting (MLC4)

Subcellular Location

Plasma membrane,Cell Junctions

Tissue Specificity

Detected in skeletal muscle. Detected in stomach, along the glandular base region of the fundic gland (at protein level). Detected in brain, lung and skeletal muscle, and at much lower levels in heart and ovary.

Cell Type

Astrocytes

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