Anti-APP Monoclonal Antibody (Solanezumab)

Subcat	Description	Isotype	Conjugate	Price
ASPC906	Anti-APP Antibody (Solanezumab)	Human IgG1, Kappa	None	$460	Add
ASPC906-A	Anti-APP Antibody (Solanezumab), APC	Human IgG1, Kappa	APC	$980	Add
ASPC906-B	Anti-APP Antibody (Solanezumab), Biotin	Human IgG1, Kappa	Biotin	$680	Add
ASPC906-H	Anti-APP Antibody (Solanezumab), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC906-P	Anti-APP Antibody (Solanezumab), PE	Human IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC906

Anti-APP Antibody (Solanezumab)

Human IgG1, Kappa

None

$460

Add

ASPC906-A

Anti-APP Antibody (Solanezumab), APC

Human IgG1, Kappa

APC

$980

Add

ASPC906-B

Anti-APP Antibody (Solanezumab), Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC906-H

Anti-APP Antibody (Solanezumab), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC906-P

Anti-APP Antibody (Solanezumab), PE

Human IgG1, Kappa

$1,180

Add

Anti-APP Monoclonal Antibody (Solanezumab)
- Product Description:
  
  The Anti-APP antibody is a human monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, functional assay and other applications. This antibody specifically targets APP and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay
  
  Target:
  
  APP
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human APP.
  
  Immunogen:
  
  Synthetic peptides (13-28 amino acids) of beta-amyloid
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  Solanezumab
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-APP Monoclonal Antibody (Solanezumab) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

APP

Protein Name

Amyloid-beta precursor protein

Introduction

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Alternative Names

AAA; ABETA; ABPP; AD1I; CTFgamma; CVAP; PN-II; PN2; APP

Gene ID

351

UniProt

P05067

Subcellular Location

Cell membrane

Cell Line Specificity

Low cancer specificity

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