Anti-APOL1 Monoclonal Antibody (F-7H8)

Anti-APOL1 Monoclonal Antibody (F-7H8)

Cat No: ASZ1C145

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
F-7H8
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C145 Anti-APOL1 Antibody (F-7H8) Mouse IgG None $460
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  • Anti-APOL1 Monoclonal Antibody (F-7H8)
    • Product Description:
      The Anti-APOL1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human APOL1.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      APOL1
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Apolipoprotein L1 (APOL1).
      Clonality:
      Monoclonal
      Clone ID:
      F-7H8
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-APOL1 Monoclonal Antibody (F-7H8) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Apolipoprotein L1
Introduction
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
Alternative Names
APO-L; APOL; APOL-I; FSGS4
Gene ID
UniProt
Related Disease
Focal segmental glomerulosclerosis 4 (FSGS4)
Subcellular Location
Secreted.
Tissue Specificity
Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
Cell Line Specificity
Cancer enhanced
Function
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
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