Anti-APOB Monoclonal Antibody (MabB23)

Subcat	Description	Isotype	Conjugate	Price
ASPC903	Anti-APOB Antibody (MabB23)	Mouse IgG2b, Lambda	None	$460	Add
ASPC903-A	Anti-APOB Antibody (MabB23), APC	Mouse IgG2b, Lambda	APC	$980	Add
ASPC903-B	Anti-APOB Antibody (MabB23), Biotin	Mouse IgG2b, Lambda	Biotin	$680	Add
ASPC903-H	Anti-APOB Antibody (MabB23), HRP	Mouse IgG2b, Lambda	HRP	$600	Add
ASPC903-P	Anti-APOB Antibody (MabB23), PE	Mouse IgG2b, Lambda	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC903

Anti-APOB Antibody (MabB23)

Mouse IgG2b, Lambda

None

$460

Add

ASPC903-A

Anti-APOB Antibody (MabB23), APC

Mouse IgG2b, Lambda

APC

$980

Add

ASPC903-B

Anti-APOB Antibody (MabB23), Biotin

Mouse IgG2b, Lambda

Biotin

$680

Add

ASPC903-H

Anti-APOB Antibody (MabB23), HRP

Mouse IgG2b, Lambda

HRP

$600

Add

ASPC903-P

Anti-APOB Antibody (MabB23), PE

Mouse IgG2b, Lambda

$1,180

Add

Anti-APOB Monoclonal Antibody (MabB23)
- Product Description:
  
  The antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, western blot and other applications. This antibody specifically targets APOB and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Source:
  
  Mouse
  
  Target:
  
  APOB
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human APOB.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  MabB23
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-APOB Monoclonal Antibody (MabB23) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

APOB

Protein Name

Apolipoprotein B-100

Introduction

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Alternative Names

FLDB; LDLCQ4; apoB-100; apoB-48

Gene ID

338

UniProt

P04114

Subcellular Location

Cytoplasm

Cell Line Specificity

Cancer enriched

Function

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.

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