-
Anti-APOA1 Monoclonal Antibody (MabA34)
-
Product Description:The Anti-APOA1 antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay and other applications. This antibody specifically targets APOA1 and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent AssayTarget:APOA1Target Species:HumanSpecificity:This antibody reacts with Human APOA1.Immunogen:Human APOA1Clonality:MonoclonalClone ID:MabA34Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECConcentration:1 mg/mLForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
-
-
Anti-APOA1 Monoclonal Antibody (MabA34) Applications
-
Note:Optimal dilutions/concentrations should be determined by the end user.
-
Gene Symbol
APOA1
Protein Name
Apolipoprotein A-I
Introduction
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
Alternative Names
apo(a)
Gene ID
UniProt
Subcellular Location
Secreted.
Tissue Specificity
Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking.
Cell Line Specificity
Group enriched
Function
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
Customer Reviews
There are no reviews for Product Name.
Submit a review and receive an Amazon gift card.
Publications
There are no publications for Product Name.
If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward
