Anti-AMA1 Monoclonal Antibody (F8.12.19)

Anti-AMA1 Monoclonal Antibody (F8.12.19)

Cat No: ASPC131

Summary
Host Species:
Mouse
Species Reactivity:
Plasmodium spp
Applications:
Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Western Blot, Immunofluorescence
Clone ID:
F8.12.19
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC131 Anti-AMA1 Antibody (F8.12.19) Mouse IgG2b, Kappa None $460 In stock
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ASPC131-P Anti-AMA1 Antibody (F8.12.19), PE Mouse IgG2b, Kappa PE $1,180 2-3 weeks
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ASPC131-A Anti-AMA1 Antibody (F8.12.19), APC Mouse IgG2b, Kappa APC $980 2-3 weeks
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ASPC131-H Anti-AMA1 Antibody (F8.12.19), HRP Mouse IgG2b, Kappa HRP $600 2-3 weeks
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ASPC131-B Anti-AMA1 Antibody (F8.12.19), Biotin Mouse IgG2b, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-AMA1 Monoclonal Antibody (F8.12.19)
    • Product Description:
      The F8.12.19 monoclonal antibody was generated against the recombinant ectoplasmic region of Apical Membrane Antigen 1 (AMA1) from Plasmodium vivax. It demonstrates cross-reactivity with AMA1 homologues from multiple Plasmodium species, including Plasmodium knowlesi, Plasmodium cynomolgi, Plasmodium berghei, and Plasmodium falciparum.
      Applications:
      Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Western Blot, Immunofluorescence
      Source:
      Mouse
      Target:
      AMA1
      Specificity:
      The antibody recognizes a discontinuous epitope on Domain III of the ectoplasmic region of AMA1.
      Immunogen:
      Plasmodium vivax AMA1
      Epitope:
      Conformational epitope
      Clonality:
      Monoclonal
      Clone ID:
      F8.12.19
      Isotype:
      Mouse IgG2b, Kappa
      Purification:
      The antibody was purified by Protein A.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for customized product form or formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-AMA1 Monoclonal Antibody (F8.12.19) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
ama-1
Protein Name
Apical merozoite antigen 1
Introduction
Apical Membrane Antigen 1 (AMA1) is a critical protein found on the surface of apicomplexan parasites, most notably Plasmodium spp., which are responsible for malaria. AMA1 plays a pivotal role in the parasite's ability to invade host cells, making it a significant target for vaccine development. AMA1 is a type I transmembrane protein, composed of an extracellular domain, a single transmembrane domain, and a short cytoplasmic tail. The extracellular domain, which is the main functional part of the protein, is highly conserved and consists of three distinct domains (D1, D2, and D3) that fold into a complex structure essential for its role in host cell invasion.
Alternative Names
AMA1; Apical merozoite antigen 1; Apical membrane antigen 1
UniProt
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