Anti-AHCY Monoclonal Antibody (C-16D12)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C83	Anti-AHCY Antibody (C-16D12)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C83

Anti-AHCY Antibody (C-16D12)

Mouse IgG

None

$460

Add

Anti-AHCY Monoclonal Antibody (C-16D12)
- Product Description:
  
  The Anti-AHCY antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human AHCY.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  AHCY
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Adenosylhomocysteinase (AHCY).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C-16D12
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-AHCY Monoclonal Antibody (C-16D12) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Adenosylhomocysteinase

Introduction

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Names

SAHH; adoHcyase

Gene ID

191

UniProt

P23526

Related Disease

Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)

Subcellular Location

Cytoplasm

Cell Line Specificity

Low cancer specificity