Anti-AGT Monoclonal Antibody (KAA8)

Subcat	Description	Isotype	Conjugate	Price
ASPC884	Anti-AGT Antibody (KAA8)	Mouse IgG1, Kappa	None	$460	Add
ASPC884-A	Anti-AGT Antibody (KAA8), APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC884-B	Anti-AGT Antibody (KAA8), Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC884-H	Anti-AGT Antibody (KAA8), HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC884-P	Anti-AGT Antibody (KAA8), PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC884

Anti-AGT Antibody (KAA8)

Mouse IgG1, Kappa

None

$460

Add

ASPC884-A

Anti-AGT Antibody (KAA8), APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC884-B

Anti-AGT Antibody (KAA8), Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC884-H

Anti-AGT Antibody (KAA8), HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC884-P

Anti-AGT Antibody (KAA8), PE

Mouse IgG1, Kappa

$1,180

Add

Anti-AGT Monoclonal Antibody (KAA8)
- Product Description:
  
  The Anti-AGT antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay and other applications. This antibody specifically targets AGT and demonstrates reactivity with Rat, Human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  AGT
  
  Specificity:
  
  This antibody reacts with AGT.
  
  Immunogen:
  
  Angiotensin II
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  KAA8
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-AGT Monoclonal Antibody (KAA8) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

AGT

Protein Name

Angiotensinogen

Introduction

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternative Names

ANHU; SERPINA8

Gene ID

183

UniProt

P01019

Subcellular Location

Secreted

Tissue Specificity

Expressed by the liver and secreted in plasma.

Cell Line Specificity

Cancer enriched

Function

Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.

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